Monday, August 19, 2019
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Innovation That Matters

The Peculiarity of Cancer Metastasis may be the Key to Controlling the Disease

Researchers at the National Institutes of Health (NIH) are taking a different approach to treating cancer, focusing on the disease’s deadly and perplexing process of metastasis, the migration of tumor cells beyond their original site. “There is no single drug approved for targeting (cancer) metastasis,”...

Expanding the Target Universe and the Therapeutic Opportunities of Small Molecules Through Covalency – Previously Thought Impossible

By Rich Soll (Senior Advisor, Strategic Initiatives, WuXi AppTec (@richsollwx). The current repertoire of tools suitable to interrogate biology and to translate this into therapeutic opportunities has been confined generally to small molecules and biologicals – although new approaches including gene editing and RNA-based technologies...

Towards the Realization of a Dream: Ending the Rare Disease Neurofibromatosa, a Conversation with the Children’s Tumor Foundation’s President Annette Bakker, Ph.D.

By Rich Soll (Senior Advisor, Strategic Initiatives, WuXi AppTec (@richsollwx). The mission of the Children’s Tumor Foundation (CTF) reads “drive research, expand knowledge, and advance care for the neurofibromatosis (NF) community.”  Sounds simple, yet despite disease complexity, this research-oriented foundation is making substantial progress towards...

Bellicum is designing a Double-Barrel, Next Generation CAR-T Therapy to Take on Pancreatic Cancer

Cancer of the pancreas is a deadly disease. It is rarely diagnosed at early stages where treatment could be more helpful, and there are few effective treatments for patients with advanced disease. So far, academic and industry research has failed to find a solution...

RNA-Focused Drug Development Emerging as a Dominant Treatment Modality

The surging scientific excitement surrounding RNA therapeutics is a little like realizing you can pick fruit off a tree without cutting it down, or pick a flower without uprooting the plant. In other words, RNA therapeutics manipulate the translation of genetic instructions as opposed to...

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WuXi STA Shanghai & Changzhou Facilities Pass U.S. FDA Inspections

SHANGHAI, 24 July, 2019: STA Pharmaceutical Co., Ltd., (WuXi STA) – a subsidiary of WuXi AppTec – announces that its Analytical Service Unit (ASU) in...