Congratulations to the scientists at deCODE genetics on their publication of the largest-ever set of human genomes from a single population and the consequent insights into mutation, evolution, gene function and disease predisposition. The studies – published today online in Nature Genetics – are built around the most comprehensive population-wide tally to date of sequences variation. They provide the largest and most detailed set of common as well as rare allele frequencies, critical for advancing more efficient diagnostics; a population-wide collection of human knockouts; and new risk factors for Alzheimer’s and a range of other diseases. deCODE and Amgen are expanding the scientific power of their own findings by enabling other to build on this work. deCODE’s informatics platform is now available at WuXi NextCODE Genomics.