In the long journey of novel drug development, time is a critical variable that can determine success or failure. For a company developing an innovative therapy, reaching key milestones at the right time not only can affect the fate of the molecule but also determine how soon patients can gain access to hope and life-saving treatment...

WuXi AppTec helped a client reach a key development milestone by applying integrated expertise to advance a dual-targeting, divalent siRNA–GalNAc conjugate from the preclinical candidate compound (PCC) to investigational new drug (IND) submission within 8 months. Rapid IND readiness was achieved not just by solving synthesis and analytical challenges, but by running process development, analytical development, and manufacturing in parallel rather than sequentially...

WuXi TIDES, an integral part of WuXi AppTec that provides solutions for oligonucleotides, peptides and related synthetic conjugates, accelerated late-stage development and commercial readiness of an innovative oligonucleotide medicine through process robustness, Quality by Design (QbD), and cost efficiency...

Q2 2026 marked a shift from promise to proof for induced proximity medicines. The first regulatory approval of a proteolysis-targeting chimera and positive Phase 3 data for a molecular glue degrader strengthened confidence in the field, while clinical programs continued to move beyond oncology into immune-mediated, inflammatory, and neurological diseases...

As drug resistance increasingly threatens the durability of antibody-drug conjugate (ADC) therapies, WuXi Biology, a segment of WuXi AppTec, is addressing this key hurdle through its ADC resistance model platform, which features a diverse panel of resistant cell lines. These capabilities enable clients to unravel resistance pathways, optimize next-generation ADC candidates, and ultimately deliver greater benefit to cancer patients worldwide...

Steroid compounds hold an important position in modern drug discovery and development, from the introduction of cortisone in the 1940s for rheumatoid arthritis, to the advent of the oral contraceptive pill, which transformed reproductive health and the lives of millions of people. Today, steroids remain widely used in the treatment of cancer, immune disorders, and metabolic diseases...